Alzheimer’s is a progressive mental illness that is caused by the degeneration of nerve cells in the brain and a brief decrease in brain mass. It is also known as the most common form of dementia, as manifested by memory loss, disorientation and the cognitive impairment.
It is estimated that only in the United States over 5.4 million people suffer from this disease; more worrying is that this figure could rise to 16 million by 2050. Because it is so difficult to treat, the impact affects not only the patient but also his family, friends and caregivers.
The big problem is getting worse as time passes and may be increasingly difficult to understand. At the moment there is no 100% effective treatment to treat it, but researchers continue poring over everything related to this disease. In the research latest, 31 scientists from the Autonomous University of Madrid (UAM) and the Center for Molecular Biology “Severo Ochoa” found that may have a relationship with the herpes virus.
The data published in the Journal of Alzheimer’s Disease focus the interest of experts in a possible cause that has been neglected and could have much to do with increased risk.
People who develop Alzheimer’s disease present in their brains two features in particular: the first is a senile plaques are composed of aggregates of beta-amyloid peptide and the other is about intracellular fibrillary tangles containing protein called tau, aggregated and phosphorylated abnormally.
Hyperphosphorylation of tau protein is one of the most influential in the progress of the factors disease, because as you go along leads to neuronal death. According to this latest research, there may be a relationship between infection caused by the herpes virus and phosphorylation of tau protein.
According to the report, “the first studies of HSV1 (herpes) in Alzheimer’s disease were conducted about three decades ago.” Since then, several studies have focused on re – evaluate the link between the virus and this progressive mental illness.
In the most recent findings it was determined that the infection of the brain by HSV1 and reactivations can cause various effects at a cognitive level, in the long term; contribute to the neuronal death characteristic of Alzheimer’s. This virus causes damage in several regions of the central nervous system associated with memory, which would be closely related to the risk of this disease.
However, the lack of hard evidence the issue has been described as controversial, according to several specialists. Despite this, the leaders of this research say that you cannot ignore these tests.
It is often ignored that microbes can remain dormant in the body in order to recover even years after the initial infection. Thus, many may be infected but asymptomatic shown until the microorganism is stimulated again.
The report adds that the use of drugs antimicrobials can reduce the formation of senile plaques, although no a drug that works as expected. The study concluded that the prevalence of the disease occurs in adults over 65 years and begins from causes that are unknown to science.
The herpes simplex virus may have much to do, but it is crucial that patients also analyze other factors such as the presence of the gene encoding ApoE4. The idea is to expand research to confirm this relationship and establish whether the virus may also be involved in other progressive neurological diseases.